Showing posts with label New England Journal of Medicine. Show all posts
Showing posts with label New England Journal of Medicine. Show all posts

Thursday, January 21, 2010

Transcendental Metaworry



Last night, worrying about the storm and our old trees, my mother, Haiti, the Senate results in Massachusetts, and a half-dozen other things, I remembered Lewis Thomas’s essay on Transcendental Metaworry in his book The Medusa and the Snail.

His only half-joking premise was that worrying is a form of prayer, and that rather than avoid it, we should make it into a discipline and get really good at it.

After I found the book and blew the dust off it, I was once again drawn in to the mind of Lewis Thomas, who might have written the book yesterday instead of in 1974.

Most of the essays in Thomas’s books originally appeared in the New England Journal of Medicine, but their subject matter was wide-ranging. He wrote about the United States health care system, about cloning, hypochondria, extra-terrestrial life, warts (“warts are wonderful structures”), music, meddling, language.

Lives of a Cell (Notes of a Biology Watcher, 1974) was the first Thomas book I read. Ann Woodlief’s Dictionary of Literary Biography, Volume 275, says that in this book Thomas “builds on the analogy between the workings of the cell and the workings of the earth and its lives, including man’s.”

Thomas’s point of view was Mozartean, a synthesis, an overview, expressed in optimistic terms without denying that we do not live in the best of all possible worlds.

By the time Thomas wrote Late Night Thoughts on Listening to Mahler’s Ninth Symphony, his point of view had become darker: He spoke about the possibility of nuclear war and called the nationalism which divides humans as “probably the most stupefying example of biological error since the age of the great reptiles, wrong at every turn, but always felicitating itself loudly.”

In The Fragile Species, 1992, Thomas’s final book, he expressed the need for some “powerful steadying cohesive force” to bring about what he called not peace, but rather “the comity of nations.” As in previous books, he spoke of the earth as a living organism whose cells include us, with a “vast wiring diagram that maintains the interconnectedness and interdependence of all its numberless parts, and the ultimate product of the life: more and more information.”

Thursday, April 9, 2009

The Cold Room Diet


I have lost 20 pounds this past year. I am healthy as far as I know and have made no changes to my diet, but it has been an unusually cold and windy year on the Coastside. Now it seems that there is a relationship between being cold and losing weight.

The New England Journal of Medicine, quoted in today's New York Times, says the answer is brown fat. Nearly every adult, the paper says, has blobs of brown fat, so called because it is filled with iron-rich mitochondria, our cells' little energy sources. PET-CT scans show that brown fat burns glucose when activated by the cold.

In other words, you can lose weight by sitting in what the paper calls a chilly room, 61 to 66 degrees (the average temperature in my historic but uninsulated redwood house).

We have insulated curtains, vinyl film on the windows, draft-stoppers on the windowsills, sheets of styrofoam glued to the walls, a thick rug on the tile floor. I have caulked everything caulkable, and still we have to wear heavy sweaters indoors. I won't even tell you what we wear to bed, but you might think of eskimos.

I suppose it is some consolation that we can keep on slathering butter on everything and still button our jeans, but it's, well, cold comfort at best.